IGF-1LR 1MG
IGF-1LR (Insulin-like Growth Factor 1 Long Recombinant) is a research-grade peptide derived from the recombinant DNA technology of human IGF-1 with a modified C-terminal extension, designed for applications in academic and industrial research settings. This peptide is synthesized to explore potential interactions in biological, pharmacological, and biochemical studies without therapeutic or human consumption claims.
Research Context
IGF-1 is a key anabolic hormone with well-documented roles in growth, development, and metabolic regulation. The long form of IGF-1, IGF-1LR, retains its biological activity while offering researchers a means to investigate structural variants, binding affinities, and potential functional differences compared to native IGF-1. This variant is often used in studies examining protein engineering, signal transduction pathways, and cellular responses under controlled experimental conditions.
Research Overview
IGF-1LR is a recombinant peptide engineered to include a C-terminal extension, extending beyond the canonical 176 amino acids of endogenous IGF-1. This modification is typically intended to enhance stability, alter receptor binding specificity, or enable novel functional studies. Due to its distinct sequence, IGF-1LR is valuable for research investigating protein-protein interactions, receptor-mediated signaling, and the biochemical properties of IGF-1 variants.
Key Research Focus Areas
- Protein Engineering Studies: Exploration of structural modifications to IGF-1 for improved stability, binding affinity, or therapeutic potential in research contexts.
- Receptor Signaling Pathways: Investigation of how IGF-1LR interacts with IGF-1 receptors (IGF-1R) compared to native IGF-1, including downstream signaling mechanisms.
- Cellular Uptake and Metabolism: Analysis of IGF-1LR’s cellular behavior, including degradation rates, receptor internalization, and effects on intracellular signaling cascades.
- Biochemical Characterization: Assessment of enzymatic activity, stability in physiological environments, and interactions with binding proteins or antibodies.
- Industrial and Synthetic Biology Applications: Potential use in large-scale production systems or as a model peptide for other recombinant protein studies.
Important Disclaimer
This product is for research use only and is intended solely for academic and industrial research applications. It is not intended for human or animal consumption, therapeutic use, or any other purpose outside of authorized research protocols. Always follow established ethical guidelines and regulatory requirements when handling peptides in research settings. Ensure compliance with applicable laws, institutional policies, and any local or international standards governing research materials.
For research use only. Not for human or animal consumption.
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